Jamie Northup

Research Associate II

Jamie Northup

“Don’t adventures ever have an end? I suppose not. Someone else always has to carry on the story.”

—Bilbo Baggins, The Fellowship of the Ring (J.R.R. Tolkien)

BA, General Biology, Pine Manor College
Current Affiliation
Social Media

Jamie has been able to gain significant hands-on experience in both academic and industrial research environments. During her undergraduate research experience she assessed whether three proteins, canonically involved in regulating 3’ end processing of mRNA and the activity of RNA polymerase II, had novel roles in DNA damage response.

After graduating, Jamie obtained a post-baccalaureate fellowship at New England Biolabs. There, she assisted in characterizing a novel, high-fidelity in vitro transcription enzyme variant, gaining a deeper understanding of the molecular biology and biochemistry of mRNA synthesis, as well as learning how to use this naturally occurring biosynthetic process for downstream experiments.

Her other experiences include working as a Research Associate for a gene therapy start-up company, Ultragenyx, where she was responsible for 1) cloning adenovirus helper genes into a plasmid, and 2) designing an AAV titer assay to be used at a production scale. Recently, Jamie was a Research Associate at Vertex Pharmaceuticals on two projects. The first employed patented derived neuron stem cells to model a genetic form of autism, using high content imaging to assess the efficacy of novel therapeutic approaches for this detrimental disorder. The second project looked at the effects of small compounds on certain molecular functions; Jamie helped with the early platform building by cloning different constructs and developing high throughput screening assays.

Jamie is excited to be joining Dewpoint to help further expand the knowledge and understanding of what condensates can do in the world of drug discovery and medicine. Other than that, she is just a nerd for all things science, Tolkien-like fantasy, horror films, and the outdoors. She enjoys volunteering, particularly giving back to young scientists and patient advocacy for young adults affected by cancer.

Jamie Northup - climbing
I enjoy those moments outdoors where you question what on earth did you get yourself into?
Jamie Northup - candid
This is me watching a friend off screen tell me a corny joke, that I tried to stop myself from laughing at.