Thomas Durand-Reville

As Vice President, Chemistry and Biophysical Sciences for Dewpoint, Thomas is building the drug discovery team in Boston and supporting various drug discovery programs across multiple disease areas.

Thomas received his Ph.D. in Chemistry from the Université Pierre et Marie Curie in Paris. After postdoctoral research at the University of Cambridge, Thomas started his medicinal chemistry career at Biogen and Wyeth where he worked on several oncology and inflammation projects.

Later, in the AstraZeneca Infection group, he was responsible for the medicinal chemistry strategy on many programs from early stage hit identification through IND-enabling studies.

These efforts culminated in the discovery of durlobactam (which recently completed Phase 3 clinical trials). He then became the head of chemistry at Entasis Therapeutics (a spin-off from the AstraZeneca Infection department), where his group focused on delivering a portfolio of innovative new antibiotics against multidrug-resistant Gram-negative pathogens.