Scientist/Sr. Scientist, Condensate Platform Assay Development

Boston, MA, USA

Dewpoint Therapeutics is building a highly collaborative team to harness the power of biomolecular condensates. Together, we are leveraging a transformative shift in the understanding of cellular biology to discover and advance breakthrough therapeutics for the toughest diseases

We are searching for a Scientist/Senior Scientist to join our Condensate Platform – Biochemistry team to drive assay development and implementation of new technologies for the characterization of biomolecular condensate structure-function relationship. The successful candidate will be responsible for developing in vitro and in cellulo condensate assays and interrogating the mechanism of action of small molecule modulators of disease condensates. Must have a strong scientific background in cellular biology, molecular biology, and biochemistry and in investigating mechanisms of action and experience in optimizing and validating assays for phenotypic and functional characterization of protein and/or RNA complexes. 

In this position you’ll be part of an energizing and supportive startup culture engaged in continuous learning, and part of an exceptional international team. This role is based at our site in Boston's Seaport district. Dewpoint offers competitive salary and benefits.

 In this role you will…

  • Develop concepts and technological capabilities that will be leveraged to bring lifesaving therapies to patients
  • Collaborate in cross-functional teams
  • Mentor junior scientists 
  • Become a valuable contributor to other initiatives as they arise in our fast paced, start up environment

To do that you will need…

  • Minimum PhD degree in Biochemistry, Cell Biology, Biophysics, or relevant field
  • Minimum 0-2 years post-degree professional experience, preferably in industry
  • 3-5 years experience with recombinant protein characterization, cell biology, enzymology, assay development and validation, and data analytics
  • Experience motivating and mentoring
  • Demonstrated ability to independently drive scientific projects
  • Ability to collaborate in a multidisciplinary and dynamic environment and experience in mentoring and leading scientific teams
  • Ability to communicate effectively in English, the shared language of our multicultural team

It is nice but not essential that you also have…

  • Experience with biomolecular condensates
  • Pharmaceutical drug discovery experience in developing cell-based and in vitro assays, supporting lead optimization programs, and performing biochemical and cellular mechanism of action
  • Experience with proteomics and/or transcriptomics
  • Experience in drug discovery
About Dewpoint
Dewpoint Therapeutics is the first company founded to apply the emerging discipline of biomolecular condensates to drug discovery. Dewpoint believes that a vast range of conditions have pathways that are regulated by condensates or arise from the dysfunction of condensates — including cancer, neurodegeneration, and metabolic disease. Dewpoint scientists are working in Boston, MA, and Dresden and Berlin, Germany, to translate condensate biology into treatments for the toughest diseases.
Dewpoint strives to cultivate an inclusive international community that welcomes and empowers everyone. We reject racism, discrimination, harassment, brutality, and all other manifestations of hate. We draw strength from diversity.

Dewpoint is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or veteran status.