We translate condensate biology into much-needed medicines.

Many vital cellular functions occur within biomolecular condensates

These droplets form dynamically throughout the cell via a process called phase separation. Their behavior is governed by weak multivalent interactions between proteins and nucleic acids.

Condensates compartmentalize and concentrate molecules, enabling key biochemical processes.

Aberrant condensates drive many diseases

When something goes awry with a condensate’s composition or behavior, we call it condensatopathy.

Condensatopathies can sequester proteins needed elsewhere in the cell, exclude proteins needed for critical processes, or have altered physical properties that lead to toxic gain of function.

C-mods treat the condensatopathies that drive disease

Condensate modulators (c-mods) are uniquely designed to hit condensate targets and reverse condensatopathies by:

• preventing harmful protein sequestration
• driving key components back into condensates
• restoring healthy condensate properties and function